Mouse Atrial Natriuretic Peptide (ANP) CLIA Kit
643.5€ (96 tests)
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name
Mouse Atrial Natriuretic Peptide (ANP) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196095
tested applications
CLIA
Description
Mouse Atrial Natriuretic Peptide (ANP) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Atrial Natriuretic Peptide (ANP).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Atrial Natriuretic Peptide (ANP) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Test Range | 7.81 pg/ml - 500 pg/ml |
| Sensitivity | 4.69 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | NPPA,ANF,ANP,ATFB6,Atrial natriuretic factor |
| Background | CLIA Kits ANP |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Atrial Natriuretic Peptide (ANP) is a hormone secreted primarily by cardiac atrial myocytes in response to increased blood volume or pressure, playing a pivotal role in cardiovascular and fluid homeostasis. ANP exerts its effects by binding to natriuretic peptide receptor-A (NPR-A), leading to increased intracellular cyclic guanosine monophosphate (cGMP) levels, which mediate vasodilation and natriuresis. This hormone reduces systemic vascular resistance and promotes sodium and water excretion in the kidneys, thereby lowering blood pressure and blood volume. ANP is also a critical regulator of the renin-angiotensin-aldosterone system (RAAS), counteracting the effects of angiotensin II and aldosterone to prevent fluid overload. Clinically, elevated ANP levels are observed in conditions like heart failure and atrial fibrillation, serving as a biomarker for these diseases. Therapeutically, recombinant ANP and analogs are being explored for their potential in treating acute decompensated heart failure and hypertension. Research also highlights ANP’s role in protecting against cardiac hypertrophy, fibrosis, and remodeling, emphasizing its broader significance in cardiovascular health and disease management.
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