Mouse ATP Binding Cassette Subfamily G Member 8 (ABCG8) Protein
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Description
Mouse ABCG8 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Subfamily G Member 8 (ABCG8) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 34.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Gln272 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9DBM0 |
| Alias | GBD4,STSL,STSL1 |
| Background | Protein ABCG8 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ABCG8 is a membrane-bound transporter belonging to the ABCG subfamily and works as a heterodimer with ABCG5. Expressed mainly in the liver and intestine, it plays a critical role in regulating sterol transport, particularly in the excretion of cholesterol and plant sterols into bile. ABCG8 helps maintain sterol homeostasis and prevent excess sterol absorption. Mutations in ABCG8 are associated with sitosterolemia, leading to sterol accumulation and increased cardiovascular risk. This transporter is crucial for lipid metabolism and overall sterol balance.
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ATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody
ABCG8 Antibody is a Rabbit Polyclonal antibody against ABCG8. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
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ATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody
Rabbit Polyclonal against the ABCG8 protein.
Ver ProductoATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody
ABCG8 Antibody is a Rabbit Polyclonal antibody against ABCG8.
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