Mouse ATP Binding Cassette Subfamily G Member 8 (ABCG8) Protein
221€ (10 µg)
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Name
Mouse ATP Binding Cassette Subfamily G Member 8 (ABCG8) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx650407
Tested Applications
WB, SDS-PAGE
Description
Mouse ABCG8 Protein is a recombinant Mouse protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Subfamily G Member 8 (ABCG8) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Gln272 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 34.0 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9DBM0 |
| Alias | GBD4,STSL,STSL1 |
| Background | Protein ABCG8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
ABCG8 is a membrane-bound transporter belonging to the ABCG subfamily and works as a heterodimer with ABCG5. Expressed mainly in the liver and intestine, it plays a critical role in regulating sterol transport, particularly in the excretion of cholesterol and plant sterols into bile. ABCG8 helps maintain sterol homeostasis and prevent excess sterol absorption. Mutations in ABCG8 are associated with sitosterolemia, leading to sterol accumulation and increased cardiovascular risk. This transporter is crucial for lipid metabolism and overall sterol balance.
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