Mouse ATP Binding Cassette Subfamily G Member 5 (ABCG5) Protein
247€ (10 µg)
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Name
Mouse ATP Binding Cassette Subfamily G Member 5 (ABCG5) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx650406
Tested Applications
WB, SDS-PAGE
Description
Mouse ABCG5 Protein is a recombinant Mouse protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Subfamily G Member 5 (ABCG5) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Asp66-Gly276 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 27.2 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99PE8 |
| Alias | STSL,STSL2,Sterolin 1 |
| Background | Protein ABCG5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
ABCG5 is an integral membrane protein and part of the ATP-binding cassette (ABC) transporter family, specifically subfamily G. Expressed primarily in the liver and intestines, ABCG5 works in tandem with ABCG8 to regulate dietary sterol absorption and biliary sterol excretion. It plays a vital role in maintaining cholesterol and plant sterol homeostasis. Mutations in ABCG5 are linked to sitosterolemia, a rare autosomal recessive disorder characterized by hyperabsorption of plant sterols and cholesterol. Its function is essential for reducing sterol accumulation and preventing cardiovascular diseases.
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