Mouse ATP Binding Cassette Subfamily G Member 5 (ABCG5) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein ABCG5
proveedor
Abbexareference
abx650406Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ABCG5 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
ABCG5 is an integral membrane protein and part of the ATP-binding cassette (ABC) transporter family, specifically subfamily G. Expressed primarily in the liver and intestines, ABCG5 works in tandem with ABCG8 to regulate dietary sterol absorption and biliary sterol excretion. It plays a vital role in maintaining cholesterol and plant sterol homeostasis. Mutations in ABCG5 are linked to sitosterolemia, a rare autosomal recessive disorder characterized by hyperabsorption of plant sterols and cholesterol. Its function is essential for reducing sterol accumulation and preventing cardiovascular diseases.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
ATP Binding Cassette Subfamily G Member 5 (ABCG5)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 27.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp66-Gly276 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ABCG5
dry ice
No
availability
Shipped within 5-7 working days.
alias
STSL,STSL2,Sterolin 1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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proveedor
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P2998Tested Applications
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