Mouse ATP-binding cassette sub-family G member 8 (ABCG8) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Mouse ATP-binding cassette sub-family G member 8 (ABCG8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-binding cassette sub-family G member 8 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP-binding cassette sub-family G member 8 (ABCG8) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9DBM0 |
| Gene ID | 67470 |
| Alias | GBD4,STSL,STSL1 |
| Background | Elisa kits for ABCG8 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCG8 is a membrane-bound transporter belonging to the ABCG subfamily and works as a heterodimer with ABCG5. Expressed mainly in the liver and intestine, it plays a critical role in regulating sterol transport, particularly in the excretion of cholesterol and plant sterols into bile. ABCG8 helps maintain sterol homeostasis and prevent excess sterol absorption. Mutations in ABCG8 are associated with sitosterolemia, leading to sterol accumulation and increased cardiovascular risk. This transporter is crucial for lipid metabolism and overall sterol balance.
Related Products
ATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody
ABCG8 Antibody is a Rabbit Polyclonal antibody against ABCG8. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
Ver Producto
ATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody
Rabbit Polyclonal against the ABCG8 protein.
Ver ProductoATP Binding Cassette Subfamily G Member 8 (ABCG8) Antibody
ABCG8 Antibody is a Rabbit Polyclonal antibody against ABCG8.
Ver Producto