Mouse Apolipoprotein C-I (APOC1) CLIA Kit
Pida mas información
935106861
info@markelab.com
Precio
845€ (96 tests)
CLIA Kits APOC1
proveedor
Abbexareference
abx491288Tested Applications
CLIAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Apolipoprotein C1 (APOC1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.
Background
APOC1 is a small protein mainly associated with high-density lipoproteins (HDL), and to a lesser extent with very-low-density lipoproteins (VLDL) and chylomicrons. It is synthesized primarily in the liver and plays a crucial role in lipid metabolism by modulating the activity of lipoprotein lipase (LPL) and cholesteryl ester transfer protein (CETP). APOC1 inhibits CETP, thereby reducing the transfer of cholesteryl esters from HDL to LDL and VLDL, which promotes HDL cholesterol levels. It also regulates triglyceride metabolism by modulating lipolytic activity, thereby influencing plasma lipid homeostasis. Elevated APOC1 levels have been associated with dyslipidemia, atherosclerosis, and an increased risk of cardiovascular diseases. It may also play a role in inflammatory responses and has been linked to neurodegenerative diseases like Alzheimer’s disease, where it interacts with amyloid-beta peptides. Research indicates APOC1 has a protective role in the reverse cholesterol transport pathway, facilitating cholesterol efflux from peripheral tissues back to the liver. Genetic variations in the APOC1 gene influence plasma lipid profiles and susceptibility to metabolic disorders, including obesity and insulin resistance.
Características del producto
category
CLIA Kits
immunogen target
Apolipoprotein C-I (APOC1)
reactivity
Mouse
test range
1.25 ng/ml - 80 ng/ml
sensitivity
< 0.59 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
APOC1, Apo-CI, ApoC-I, apo-CIB, apoC-IB, apolipoprotein C1, Apolipoprotein C-I
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
APOC1
dry ice
No
uniprot id
note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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