Mouse APO-F(Apolipoprotein F) ELISA Kit

Product specifications

ELISA Kits

mouse

Colorimetric

Quantitative

Sandwich ELISA, Double Antibody

15.625-1000ng/ml

96T

Serum,Plasma,Tissue homogenates,Other biological fluids

Shipped within 10-14 working days.

2-8 °C for 6 months

Q91V80

APOF, Apo-F, LTIP, apolipoprotein F,Apo F

Elisa Kits APOF

RUO

Apolipoprotein F (APOF) is a lesser-known but essential component of the apolipoprotein family, predominantly found in high-density lipoproteins (HDL) and low-density lipoproteins (LDL). ApoF plays a regulatory role in cholesteryl ester transfer protein (CETP) activity, which facilitates the transfer of cholesteryl esters from HDL to triglyceride-rich lipoproteins like VLDL and LDL. By modulating CETP activity, ApoF influences cholesterol distribution, lipid metabolism, and the balance between HDL and LDL particles. ApoF is mainly synthesized in the liver and circulates in plasma, with elevated levels observed in dyslipidemia and cardiovascular diseases. ApoF is thought to act as a negative regulator of CETP, reducing cholesterol transfer and preserving HDL levels, which are vital for reverse cholesterol transport and cardiovascular health. Its role in maintaining HDL function positions ApoF as a potential therapeutic target in atherosclerosis and other metabolic disorders. Further research is exploring its contribution to lipid homeostasis, inflammation, and cholesterol efflux pathways, which are critical for combating cardiovascular disease and lipid-related pathologies.

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anti- APOF antibody

Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein(CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.

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