Mouse Antigen-presenting glycoprotein CD1d2 (CD1D2) ELISA Kit

Este producto es parte de CD1D - CD1d molecule
Mouse Antigen-presenting glycoprotein CD1d2 (CD1D2) ELISA Kit
715€ (96 tests)

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Name
Mouse Antigen-presenting glycoprotein CD1d2 (CD1D2) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx505738
Tested Applications
ELISA

Description

Mouse Antigen-presenting glycoprotein CD1d2 (CD1D2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Antigen-presenting glycoprotein CD1d2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Antigen-presenting glycoprotein CD1d2 (CD1D2)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P11610
Gene ID
12480
Alias
R3,CD1A,R3G1,Antigen-presenting glycoprotein CD1d
Background
Elisa Kits for: CD1D
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

CD1D is a key member of the CD1 family of glycoproteins, which are specialized antigen-presenting molecules. CD1 proteins are distinct from classical major histocompatibility complex (MHC) class I and II molecules in that they present lipid and glycolipid antigens, rather than peptide antigens, to T cells. CD1D is unique within the CD1 family because of its specialized role in presenting lipid antigens to natural killer T (NKT) cells, particularly the invariant NKT (iNKT) cells, which express a semi-invariant T cell receptor (TCR). This interaction is essential for initiating rapid immune responses against a variety of pathogens, as well as in immune regulation. CD1D is expressed predominantly on antigen-presenting cells (APCs), such as dendritic cells, macrophages, and B cells, but is also found on certain epithelial cells. Through its interaction with NKT cells, CD1D mediates a range of immune responses, including the production of cytokines that regulate the function of other immune cells, such as dendritic cells, natural killer (NK) cells, and conventional T cells. This makes CD1D important not only for pathogen defense but also for the regulation of inflammation, tolerance, and tumor immunity.

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