Mouse Anoctamin 1 (ANO1) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Anoctamin 1 (ANO1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501817
tested applications
ELISA
Description
Mouse Anoctamin 1 (ANO1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin 1 concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Anoctamin 1 (ANO1) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Sensitivity | < 0.06 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q8BHY3 |
Gene ID | 101772 |
Alias | ANO1,DOG1,ORAOV2,TAOS2,TMEM16A |
Background | Elisa kits for ANO1 |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANO1, also known as TMEM16A, is a calcium-activated chloride channel (CaCC) that plays a critical role in regulating chloride ion transport across membranes. It is widely expressed in epithelial cells, smooth muscle, and sensory neurons, where it regulates functions such as fluid secretion, smooth muscle contraction, and sensory transduction. ANO1 is essential for maintaining proper secretion of fluids and electrolytes in tissues such as the respiratory tract, salivary glands, and intestines. Dysregulation of ANO1 has been associated with diseases like cystic fibrosis, where chloride transport is impaired, as well as cancer, particularly in promoting tumor cell proliferation and migration. ANO1 also contributes to neuronal excitability and pain sensation, making it a potential therapeutic target in disorders involving abnormal ion transport and smooth muscle dysfunction.
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