Mouse Anoctamin 1 (ANO1) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ANO1
proveedor
Abbexareference
abx501817Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Anoctamin 1 (ANO1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin 1 concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
ANO1, also known as TMEM16A, is a calcium-activated chloride channel (CaCC) that plays a critical role in regulating chloride ion transport across membranes. It is widely expressed in epithelial cells, smooth muscle, and sensory neurons, where it regulates functions such as fluid secretion, smooth muscle contraction, and sensory transduction. ANO1 is essential for maintaining proper secretion of fluids and electrolytes in tissues such as the respiratory tract, salivary glands, and intestines. Dysregulation of ANO1 has been associated with diseases like cystic fibrosis, where chloride transport is impaired, as well as cancer, particularly in promoting tumor cell proliferation and migration. ANO1 also contributes to neuronal excitability and pain sensation, making it a potential therapeutic target in disorders involving abnormal ion transport and smooth muscle dysfunction.
Características del producto
category
ELISA Kits
immunogen target
Anoctamin 1 (ANO1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ANO1,DOG1,ORAOV2,TAOS2,TMEM16A
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ANO1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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