Mouse Anoctamin 1 (ANO1) ELISA Kit

Este producto es parte de ANO - Anoctamin
Mouse Anoctamin 1 (ANO1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ANO1

proveedor

Abbexa

reference

abx501817

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Anoctamin 1 (ANO1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin 1 concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


Background

ANO1, also known as TMEM16A, is a calcium-activated chloride channel (CaCC) that plays a critical role in regulating chloride ion transport across membranes. It is widely expressed in epithelial cells, smooth muscle, and sensory neurons, where it regulates functions such as fluid secretion, smooth muscle contraction, and sensory transduction. ANO1 is essential for maintaining proper secretion of fluids and electrolytes in tissues such as the respiratory tract, salivary glands, and intestines. Dysregulation of ANO1 has been associated with diseases like cystic fibrosis, where chloride transport is impaired, as well as cancer, particularly in promoting tumor cell proliferation and migration. ANO1 also contributes to neuronal excitability and pain sensation, making it a potential therapeutic target in disorders involving abnormal ion transport and smooth muscle dysfunction.

Características del producto

category

ELISA Kits


immunogen target

Anoctamin 1 (ANO1)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.06 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ANO1,DOG1,ORAOV2,TAOS2,TMEM16A


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ANO1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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