Mouse Annexin A5 (ANXA5) Protein

Este producto es parte de ANXA5 - Annexin A5
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234€ (5 µg)

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935106861
info@markelab.com
name
Mouse Annexin A5 (ANXA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680399
tested applications
SDS-PAGE

Description

Mouse Annexin A5 (ANXA5) Protein is a recombinant protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Annexin A5 (ANXA5)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: 31.4 kDa

Concentration: 1 mg/ml

Sequence Fragment: 1-266 AA

Tag: C-terminal His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
5 µg
Size 2
20 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Buffer
20 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mM PMSF and 10% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Store frozen at -20°C for longer periods of time. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ANXA5,ANX5,ENX2,PP4
Background
Protein ANXA5
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ANXA5 is a well-known calcium- and phospholipid-binding protein involved in apoptosis, membrane repair, and anti-inflammatory processes. It binds to phosphatidylserine (PS), a phospholipid exposed on the outer leaflet of apoptotic cells, making ANXA5 a widely used marker for apoptosis detection. ANXA5 regulates coagulation and fibrinolysis by preventing the assembly of coagulation complexes on cell membranes, contributing to antithrombotic activity. It is expressed in various tissues, including the placenta, where it plays roles in trophoblast function and pregnancy maintenance. Dysregulation of ANXA5 has been associated with autoimmune diseases, recurrent pregnancy loss, and cancers. Its apoptotic and anticoagulant properties make it a key protein in cellular homeostasis and disease pathology.

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