Mouse Annexin A5 (ANXA5) Protein

234€ (5 µg)
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935106861
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name
Mouse Annexin A5 (ANXA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680399
tested applications
SDS-PAGE
Description
Mouse Annexin A5 (ANXA5) Protein is a recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Annexin A5 (ANXA5) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: 31.4 kDa Concentration: 1 mg/ml Sequence Fragment: 1-266 AA Tag: C-terminal His tag |
Expression | Recombinant |
Purity | > 95% (SDS-PAGE) |
Size 1 | 5 µg |
Size 2 | 20 µg |
Size 3 | 1 mg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Buffer | 20 mM Tris-HCl, pH 8.0, 50 mM NaCl, 0.1 mM PMSF and 10% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Store frozen at -20°C for longer periods of time. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | ANXA5,ANX5,ENX2,PP4 |
Background | Protein ANXA5 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ANXA5 is a well-known calcium- and phospholipid-binding protein involved in apoptosis, membrane repair, and anti-inflammatory processes. It binds to phosphatidylserine (PS), a phospholipid exposed on the outer leaflet of apoptotic cells, making ANXA5 a widely used marker for apoptosis detection. ANXA5 regulates coagulation and fibrinolysis by preventing the assembly of coagulation complexes on cell membranes, contributing to antithrombotic activity. It is expressed in various tissues, including the placenta, where it plays roles in trophoblast function and pregnancy maintenance. Dysregulation of ANXA5 has been associated with autoimmune diseases, recurrent pregnancy loss, and cancers. Its apoptotic and anticoagulant properties make it a key protein in cellular homeostasis and disease pathology.
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