Mouse Angiopoietin-Related Protein 4 (ANGPTL4) Protein

Pida mas información
935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ANGPTL4
proveedor
Abbexareference
abx065337Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant ANGPTL4 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
ANGPTL4 is a secreted glycoprotein that plays key roles in lipid metabolism, angiogenesis, and inflammation. ANGPTL4 functions as an inhibitor of lipoprotein lipase (LPL), regulating triglyceride hydrolysis and fatty acid release, particularly during fasting and energy deprivation. It is expressed in adipose tissue, liver, and muscle, where it coordinates energy balance and lipid transport. ANGPTL4 also modulates angiogenesis by inhibiting endothelial cell proliferation and migration, making it a negative regulator of vascular growth. In cancer, ANGPTL4 has context-dependent roles, promoting metastasis by enhancing tumor cell migration and vascular permeability while inhibiting angiogenesis in certain conditions. Elevated ANGPTL4 levels are associated with obesity, diabetes, and atherosclerosis, where it contributes to dyslipidemia and chronic inflammation. Its ability to regulate lipid metabolism, angiogenesis, and inflammation makes ANGPTL4 a potential target for treating metabolic disorders, cardiovascular disease, and cancer.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Angiopoietin-Related Protein 4 (ANGPTL4)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 31.5 kDa Observed MW (SDS-PAGE): 35 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr183-Ile401 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ANGPTL4
dry ice
No
availability
Shipped within 5-7 working days.
alias
ARP4,FIAF,HARP,HFARP,NL2
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human ANGPTL4(Angiopoietin-related protein 4) ELISA Kit

proveedor
FineTestreference
EH0038reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse ANGPTL4(Angiopoietin Like Protein 4) ELISA Kit

proveedor
FineTestreference
EM0721reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- ANGPTL4 antibody

proveedor
FineTestreference
FNab00399Tested Applications
ELISA, IHC, IF, IP, WBreactivity
human,mousestatus
RUOclonality
polyclonalProtein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumori...
Precio a consultar
Ver más