Mouse Ang1 (Angiopoietin-1) ELISA Kit

Este producto es parte de ANGPT - Angiopoietin
Mouse Ang1 (Angiopoietin-1) ELISA Kit
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Name
Mouse Ang1 (Angiopoietin-1) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EM0016
Tested Applications
ELISA

Documentos del producto

Instrucciones
Descargar
Data sheet

Especificaciones del producto

Category
ELISA Kits
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
O08538
Alias
AGP1,AGPT,ANG1,HAE5,AGPT-1
Background
Elisa kits for ANGPT1
Status
RUO

Background

ANGPT1 is a secreted glycoprotein that plays a critical role in angiogenesis, the process of new blood vessel formation, and the stabilization of vascular networks. ANGPT1 binds to and activates the Tie2 receptor, a tyrosine kinase expressed on endothelial cells, leading to signaling pathways that promote endothelial cell survival, migration, and the formation of stable, mature blood vessels. ANGPT1 is essential for maintaining vascular integrity and preventing vascular leakage by enhancing cell-cell junctions and stabilizing endothelial barriers. It also counteracts pro-inflammatory signals and prevents excessive vascular permeability caused by VEGF or other stressors. ANGPT1 is involved in developmental processes such as embryonic vascular formation and tissue regeneration. Dysregulation of ANGPT1 has been implicated in vascular disorders, including chronic inflammation, edema, and cardiovascular diseases. ANGPT1’s role in maintaining vascular stability makes it a therapeutic target for diseases involving abnormal angiogenesis, such as cancer, diabetic retinopathy, and sepsis.

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