Mouse Anaphase Promoting Complex Subunit 2 (ANAPC2) ELISA Kit

Este producto es parte de ANAPC - Anaphase-promoting complex subunit
Mouse Anaphase Promoting Complex Subunit 2 (ANAPC2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ANAPC2

proveedor

Abbexa

reference

abx388576

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Anaphase Promoting Complex Subunit 2 (ANAPC2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ANAPC2 concentrations in serum, plasma and other biological fluids.


Background

ANAPC2 is a core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) and functions as part of the catalytic module that regulates its E3 ubiquitin ligase activity. ANAPC2 interacts directly with ANAPC11, the RING finger protein, and facilitates the recruitment of E2 ubiquitin-conjugating enzymes to catalyze the transfer of ubiquitin onto substrates such as cyclin B, securin, and other key cell cycle regulators. This activity ensures the timely degradation of APC/C targets, driving the metaphase-to-anaphase transition and promoting exit from mitosis. ANAPC2 is critical for maintaining chromosomal stability and proper cell cycle progression. Dysregulation of ANAPC2 impairs APC/C activity, leading to mitotic defects, aneuploidy, and genomic instability, which are associated with cancer development and progression. Its catalytic role highlights ANAPC2 as a key player in cell division and a potential therapeutic target for controlling aberrant cell proliferation in cancers.

Características del producto

category

ELISA Kits


immunogen target

Anaphase Promoting Complex Subunit 2 (ANAPC2)


reactivity

Mouse


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 46.9 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

ANAPC2,APC2,Cyclosome subunit 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ANAPC2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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