Mouse Amyloid-beta Precursor Protein (APP) ELISA Kit
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935106861
info@markelab.com
Precio
702€ (96 tests)
Elisa kits for APP
proveedor
Abbexareference
abx153667Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Amyloid-beta Precursor Protein (APP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Amyloid-beta Precursor Protein (APP) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Amyloid-beta Precursor Protein (APP)
Background
APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders
Características del producto
category
ELISA Kits
immunogen target
Amyloid-beta Precursor Protein (APP)
reactivity
Mouse
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.12 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
APP
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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