Mouse Amphoterin-induced protein 2 (AMIGO2) ELISA Kit

Este producto es parte de AMIGO - Amphoterin-induced protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Amphoterin-induced protein 2 (AMIGO2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501628
tested applications
ELISA

Description

Mouse Amphoterin-induced protein 2 (AMIGO2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Amphoterin-induced protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetAmphoterin-induced protein 2 (AMIGO2)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ80ZD9
Gene ID105827
AliasAMIGO2,ALI1,AMIGO-2,Alivin-1
BackgroundElisa kits for AMIGO2
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

AMIGO2, like AMIGO1, is a cell adhesion molecule that regulates cell migration, adhesion, and survival. It is expressed in various tissues, including the brain, heart, and vascular system, where it participates in developmental processes and cellular signaling. AMIGO2 plays a role in the maintenance of endothelial cell integrity and vascular remodeling, making it essential for blood vessel formation and repair. In the context of cancer, AMIGO2 is implicated in tumor angiogenesis and metastasis by promoting cell survival and migration through interactions with signaling pathways such as PI3K/AKT. Overexpression of AMIGO2 has been observed in cancers such as hepatocellular carcinoma and gastric cancer, where it contributes to tumor progression and resistance to apoptosis. AMIGO2 also supports neuronal survival under stress conditions, linking it to neuroprotection and repair mechanisms in the nervous system. Its role in both vascular biology and tumorigenesis makes AMIGO2 a potential therapeutic target.

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