Mouse Alpha-methylacyl-CoA racemase (AMACR) ELISA Kit

Este producto es parte de AMACR - Alpha-methylacyl-CoA racemase
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Alpha-methylacyl-CoA racemase (AMACR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx514526
tested applications
ELISA

Description

Mouse Alpha-methylacyl-CoA racemase (AMACR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alpha-methylacyl-CoA racemase concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Alpha-methylacyl-CoA racemase (AMACR)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.625 ng/ml - 40 ng/ml
Sensitivity
< 0.49 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
O09174
Gene ID
17117
Alias
AMACR
Background
Elisa kits for AMACR
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Alpha-Methylacyl-CoA Racemase (AMACR) is a mitochondrial and peroxisomal enzyme that catalyzes the racemization of alpha-methyl-branched fatty acid derivatives and bile acid intermediates, enabling their further metabolism via beta-oxidation. AMACR is critical in lipid metabolism, particularly in the breakdown of dietary branched-chain fatty acids and the processing of bile acids derived from cholesterol. It is highly expressed in tissues with active fatty acid metabolism, such as the liver and kidneys. Dysregulation or mutations in the AMACR gene are associated with metabolic disorders, including adult-onset sensory neuropathy and bile acid metabolism defects. Additionally, AMACR is a well-established biomarker for prostate cancer and other malignancies, as its overexpression is linked to cancer cell metabolism and tumor progression. Targeting AMACR enzymatic activity is being explored as a therapeutic strategy in cancer and metabolic disorders.

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