Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) ELISA Kit

Este producto es parte de AASS - Alpha-aminoadipic semialdehyde synthase mitochondrial
Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AASS

proveedor

Abbexa

reference

abx500370

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alpha-aminoadipic semialdehyde synthase, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Alpha-aminoadipic semialdehyde synthase (AASS) is a bifunctional mitochondrial enzyme involved in the lysine degradation pathway. It catalyzes two sequential reactions: the oxidation of lysine to saccharopine via its lysine-ketoglutarate reductase activity and the subsequent conversion of saccharopine to alpha-aminoadipic semialdehyde via saccharopine dehydrogenase activity. This pathway plays a crucial role in amino acid catabolism and the production of acetyl-CoA, linking it to energy metabolism and the tricarboxylic acid (TCA) cycle. AASS is essential for maintaining lysine homeostasis and energy production, particularly under conditions of low glucose availability. Mutations in the AASS gene can lead to hyperlysinemia, a metabolic disorder characterized by elevated lysine levels in the blood and associated neurological symptoms. Emerging studies suggest AASS may also play a regulatory role in mitochondrial function and oxidative stress responses.

Características del producto

category

ELISA Kits


immunogen target

Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

LKRSDH,LORSDH,LKR/SDH


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AASS


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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