Mouse Alpha-1-Antitrypsin (SERPINA1) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Mouse Alpha-1-Antitrypsin (SERPINA1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx065230
Tested Applications
WB, SDS-PAGE
Description
Mouse Alpha-1-Antitrypsin (a1AT) is a recombinant Mouse protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Alpha-1-Antitrypsin (SERPINA1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu25-Lys413 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 45.0 kDa Observed MW (SDS-PAGE): 45 kDa |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z4T9 |
| Alias | PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| Background | Protein SERPINA1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.
Productos relacionados
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-…
Ver producto
Rat Alpha-1-Antiproteinase (SERPINA1) ELISA Kit
Rat Alpha-1-Antiproteinase (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alpha-1…
Ver producto
alpha-1-Antitrypsin (SERPINA1) Antibody
SERPINA1 Antibody is a Rabbit Polyclonal against SERPINA1.…
Ver producto