Mouse Alpha-1-Antitrypsin (SERPINA1) Protein
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Recombinant Alpha-1-Antitrypsin (a1AT) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Alpha-1-Antitrypsin (SERPINA1) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 45.0 kDa Observed MW (SDS-PAGE): 45 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu25-Lys413 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z4T9 |
| Alias | PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| Background | Protein SERPINA1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.
Related Products
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-1-Antitrypsin (SERPINA1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Alpha-1-Antitrypsin (a1AT)
Ver Producto
Rat Alpha-1-Antiproteinase (SERPINA1) ELISA Kit
Rat Alpha-1-Antiproteinase (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alpha-1-Antiproteinase (SERPINA1) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Alpha-1-Antiproteinase (a1AT)
Ver Producto
alpha-1-Antitrypsin (SERPINA1) Antibody
SERPINA1 Antibody is a Rabbit Polyclonal against SERPINA1.
Ver Producto