Mouse Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168394
tested applications
WB, SDS-PAGE
Description
Aldehyde Dehydrogenase 9 Family, Member A1 Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 22.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu322-Phe494 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ALDH9A1,ALDH4,ALDH7,ALDH9 |
| Background | Protein ALDH9A1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ALDH9A1 is a cytosolic enzyme that oxidizes γ-aminobutyraldehyde (GABAL) and betaine aldehyde to their respective acids, playing a role in neurotransmitter metabolism and osmolyte synthesis. It is highly expressed in the liver, brain, and kidneys, where it supports the conversion of GABAL to GABA, an important inhibitory neurotransmitter, and the conversion of betaine aldehyde to betaine, a key osmolyte involved in cellular hydration and methylation processes. ALDH9A1’s function is critical for maintaining GABA homeostasis, osmotic balance, and methyl group donation in metabolic pathways. Dysregulation of ALDH9A1 has been associated with neurological disorders, where impaired GABA metabolism can contribute to excitotoxicity and neurodegeneration. ALDH9A1 also protects cells from aldehyde toxicity, as it detoxifies reactive intermediates generated during amino acid and lipid metabolism. Its role in neurotransmitter balance and cellular protection makes it a target for neurological and metabolic disease therapies.
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