Mouse Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) CLIA Kit

Este producto es parte de ALDH - Aldehyde dehydrogenase family member
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845€ (96 tests)

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935106861
info@markelab.com
name
Mouse Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx494761
tested applications
CLIA

Description

Mouse Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
CLIA Kits
Immunogen Target
Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.066 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
ALDH9A1,ALDH4,ALDH7,ALDH9
Background
CLIA Kits ALDH9A1
Status
RUO
Note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ALDH9A1 is a cytosolic enzyme that oxidizes γ-aminobutyraldehyde (GABAL) and betaine aldehyde to their respective acids, playing a role in neurotransmitter metabolism and osmolyte synthesis. It is highly expressed in the liver, brain, and kidneys, where it supports the conversion of GABAL to GABA, an important inhibitory neurotransmitter, and the conversion of betaine aldehyde to betaine, a key osmolyte involved in cellular hydration and methylation processes. ALDH9A1’s function is critical for maintaining GABA homeostasis, osmotic balance, and methyl group donation in metabolic pathways. Dysregulation of ALDH9A1 has been associated with neurological disorders, where impaired GABA metabolism can contribute to excitotoxicity and neurodegeneration. ALDH9A1 also protects cells from aldehyde toxicity, as it detoxifies reactive intermediates generated during amino acid and lipid metabolism. Its role in neurotransmitter balance and cellular protection makes it a target for neurological and metabolic disease therapies.

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