Mouse Adenylate Cyclase 10, Soluble (ADCY10) Protein

Este producto es parte de ADCY - Adenylate Cyclase Type
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1872€ (1 mg)

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935106861
info@markelab.com
name
Mouse Adenylate Cyclase 10, Soluble (ADCY10) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652387
tested applications
WB, SDS-PAGE

Description

Mouse Adenylate Cyclase 10, Soluble (ADCY10) Protein is a Recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetAdenylate Cyclase 10, Soluble (ADCY10)
HostE. coli
OriginMouse
ConjugationUnconjugated
Observed MWConcentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag
ExpressionRecombinant
Purity> 90%
Size 11 mg
Size 25 mg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 1-2 months.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ8C0T9
AliasHCA2,HEL-S-7a,SAC,SACI,Sacy
BackgroundProtein ADCY10
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADCY10, also known as soluble adenylate cyclase (sAC), differs from other ADCY isoforms as it is soluble and not membrane-bound. It is activated by bicarbonate ions and calcium, making it essential for pH and metabolic regulation. ADCY10 is involved in processes such as sperm motility, capacitation, and fertilization in the reproductive system. It also regulates cellular metabolism, mitochondrial respiration, and renal acid-base homeostasis. Mutations in ADCY10 have been associated with male infertility and metabolic dysfunctions, underscoring its significance in reproductive and cellular physiology.

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