Mouse Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) ELISA Kit

Este producto es parte de ACSL - Acyl-CoA Synthetase Long-Chain Family Member Elisa - Clia - Antibody - Protein
Mouse Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

728€ (96 tests)

Elisa kits for ACSL4

proveedor

Abbexa

reference

abx500882

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ACSL4 is an acyl-CoA synthetase with a strong preference for polyunsaturated fatty acids, such as arachidonic and docosahexaenoic acids, converting them into acyl-CoA derivatives for metabolic use. It is highly expressed in the brain, testis, and adrenal glands, where it supports processes requiring specialized lipid metabolism, including the biosynthesis of eicosanoids and membrane lipids. ACSL4 is critical in ferroptosis, a type of programmed cell death triggered by lipid peroxidation, through its role in incorporating polyunsaturated fatty acids into phospholipids. Dysregulation of ACSL4 has been linked to cancer, neurodegenerative diseases, and inflammatory disorders, as it influences processes such as oxidative stress and cellular survival. Its specific role in handling polyunsaturated fatty acids highlights its importance in maintaining cellular lipid balance and preventing oxidative damage under stress conditions.

Características del producto

category

ELISA Kits


immunogen target

Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4)


reactivity

Mouse


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.12 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates, cell culture supernatant and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ACS4,FACL4,LACS4 MRX63,MRX68


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ACSL4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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