Mouse Activin A Receptor Type I (ACVR1) Protein
Pida mas información
935106861
info@markelab.com
Precio
2062.5€ (1 mg)
Protein ACVR1
proveedor
Abbexareference
abx065133Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant ACVR1 (ACVR1) is a recombinant Mouse protein produced in E. coli using Prokaryotic expression.
Background
ACVR1, also called ALK2 (Activin Receptor-Like Kinase 2), is a transmembrane serine/threonine kinase receptor. It binds ligands like BMPs (Bone Morphogenetic Proteins), initiating intracellular SMAD signaling. This receptor plays a crucial role in bone development, embryogenesis, and organogenesis. Mutations in ACVR1 are linked to fibrodysplasia ossificans progressiva (FOP), a rare disorder where soft tissues progressively ossify. Structurally, it comprises an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular kinase domain.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Activin A Receptor Type I (ACVR1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
1 mg
size 2
5 mg
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACVR1
dry ice
No
availability
Shipped within 1-2 months.
alias
ACVRLK2
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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