Mouse Activated Leukocyte Cell Adhesion Molecule / CD166 (ALCAM) ELISA Kit

Este producto es parte de ALCAM - Activated leukocyte cell adhesion molecule
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585€ (96 tests)

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935106861
info@markelab.com
name
Mouse Activated Leukocyte Cell Adhesion Molecule / CD166 (ALCAM) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx254683
tested applications
ELISA

Description

Mouse Activated Leukocyte Cell Adhesion Molecule / CD166 (ALCAM) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Activated Leukocyte Cell Adhesion Molecule / CD166 (ALCAM) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetActivated Leukocyte Cell Adhesion Molecule / CD166 (ALCAM)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.156 ng/ml - 10 ng/ml
Sensitivity0.1 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ61490
AliasALCAM,MEMD,CD166
BackgroundElisa kits for ALCAM
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Activated leukocyte cell adhesion molecule (ALCAM), also known as CD166, is a cell surface glycoprotein that belongs to the immunoglobulin superfamily. It plays a significant role in cell-cell adhesion and signaling processes, particularly in the immune system and in various developmental processes. ALCAM is widely expressed in various tissues and cell types, including leukocytes, endothelial cells, neurons, and cancer cells. Its functions include: Cell-Cell Adhesion: ALCAM mediates homophilic (like-to-like) and heterophilic (different molecules) interactions between cells. It facilitates the adhesion of leukocytes to endothelial cells, which is essential for immune cell recruitment to sites of inflammation and in the immune response. Neuronal Development: ALCAM is involved in neuronal migration, axon growth, and guidance during brain development. It helps regulate the formation of neural circuits and synaptic connections. Cancer Progression: ALCAM expression has been implicated in cancer progression and metastasis. It can promote tumor cell migration, invasion, and metastasis by enhancing cell adhesion and facilitating interactions between cancer cells and the surrounding microenvironment.Stem Cell Maintenance: ALCAM is involved in the maintenance and regulation of stem cell populations in various tissues. It plays a role in stem cell adhesion, migration, and differentiation.

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