Mouse Actin Filament Associated Protein 1 (AFAP1) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein AFAP1
proveedor
Abbexareference
abx168877Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse AFAP1 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Actin Filament Associated Protein 1 (AFAP1), also known as AFAP-110 or AFAP1L1, is a cytoskeletal protein involved in the regulation of actin dynamics and cell motility. AFAP1 is a multidomain protein consisting of several functional domains, including an N-terminal BAR (Bin-Amphiphysin-Rvs) domain, a central proline-rich region, a serine-rich region, and a C-terminal SH3 (Src homology 3) domain. These domains facilitate protein-protein interactions and mediate the binding of AFAP1 to various cytoskeletal and signaling molecules. AFAP1 regulates actin cytoskeleton dynamics by interacting with actin filaments and modulating their organization and stability. It can promote actin polymerization and bundling, as well as cross-linking of actin filaments, thereby influencing cell shape, migration, and adhesion. AFAP1 also plays a role in cell motility and migration by coordinating actin cytoskeleton rearrangements necessary for cell protrusion, adhesion, and movement. It interacts with signaling proteins involved in focal adhesion turnover, cytoskeletal remodeling, and cell contractility
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Actin Filament Associated Protein 1 (AFAP1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 28.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Cys352-Glu572 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
AFAP1
dry ice
No
availability
Shipped within 5-7 working days.
alias
AFAP,AFAP110,AFAP-110
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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