Mouse Aconitase 1 (ACO1) Protein

Este producto es parte de ACO - Aconitase
Mouse Aconitase 1 (ACO1) Protein

Pida mas información

935106861

info@markelab.com

Precio

260€ (10 µg)

Protein ACO1

proveedor

Abbexa

reference

abx065105

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Aconitase 1 (ACO1) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Aconitase 1 (ACO1) is a dual-function iron-sulfur protein located in the cytoplasm, acting as both an enzyme and an iron-responsive element-binding protein (IRP1). As an enzyme, ACO1 catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid (TCA) cycle, contributing to cellular energy production. Under low iron conditions, ACO1 switches to its role as IRP1, binding to iron-responsive elements (IREs) in mRNAs to regulate the expression of genes involved in iron metabolism, such as ferritin and transferrin receptor. This functional versatility allows ACO1 to coordinate cellular energy metabolism and iron homeostasis. Dysregulation of ACO1 is implicated in disorders related to iron overload or deficiency, as well as oxidative stress-induced damage in neurodegenerative diseases.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Aconitase 1 (ACO1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 23.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val527-Met719 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ACO1


dry ice

No


availability

Shipped within 5-12 working days.


alias

IRP1,ACONS,HEL60,IREB1,IREBP,IREBP1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

Human ACO1(Aconitase 1) ELISA Kit

Human ACO1(Aconitase 1) ELISA Kit

proveedor

FineTest

reference

EH0600

reactivity

human

status

RUO

Precio a consultar

Ver más

Cytoplasmic Aconitate Hydratase (ACO1) Antibody

Cytoplasmic Aconitate Hydratase (ACO1) Antibody

proveedor

Abbexa

reference

abx004618

Tested Applications

ELISA, WB

reactivity

Mouse, Rat

status

RUO

clonality

Monoclonal

ACO1 Antibody is a Rabbit Monoclonal antibody against ACO1. The protein encoded by this gene is a bifunctional, cytosoli...

195€ (20 µl)

Ver más

Human Aconitase 1 (ACO1) Protein

Human Aconitase 1 (ACO1) Protein

proveedor

Abbexa

reference

abx065100

Tested Applications

WB, SDS-PAGE

status

RUO

Recombinant Aconitase 1 (ACO1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

273€ (10 µg)

Ver más