Mouse Acetyl Coenzyme A Acyltransferase 1 (ACAA1) Protein

Este producto es parte de ACAA - Acetyl Coenzyme A Acyltransferase
Mouse Acetyl Coenzyme A Acyltransferase 1 (ACAA1) Protein

Pida mas información

935106861

info@markelab.com

Precio

208€ (10 µg)

Protein ACAA1

proveedor

Abbexa

reference

abx650411

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse ACAA1 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Acetyl Coenzyme A Acyltransferase 1 (ACAA1), also known as thiolase, is a peroxisomal enzyme involved in the final step of beta-oxidation of very-long-chain fatty acids and branched-chain fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA and a shortened acyl-CoA, which is then further metabolized for energy production. ACAA1 is critical for lipid metabolism and plays an important role in energy homeostasis during fasting or periods of high energy demand. Dysregulation of ACAA1 activity can lead to metabolic disorders, such as Zellweger syndrome and other peroxisomal biogenesis disorders, characterized by impaired fatty acid oxidation and accumulation of toxic lipid intermediates. ACAA1 is also being studied for its role in the metabolic reprogramming of cancer cells, where it contributes to lipid catabolism and tumor progression.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Acetyl Coenzyme A Acyltransferase 1 (ACAA1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 28.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly182-Asn424 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ACAA1


dry ice

No


availability

Shipped within 5-7 working days.


alias

ACAA, Lnc-Myd88, PTHIO, THIO


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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