Mouse Acetyl Coenzyme A Acyltransferase 1 (ACAA1) Protein
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935106861
info@markelab.com
Precio
208€ (10 µg)
Protein ACAA1
proveedor
Abbexareference
abx650411Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ACAA1 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Acetyl Coenzyme A Acyltransferase 1 (ACAA1), also known as thiolase, is a peroxisomal enzyme involved in the final step of beta-oxidation of very-long-chain fatty acids and branched-chain fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA and a shortened acyl-CoA, which is then further metabolized for energy production. ACAA1 is critical for lipid metabolism and plays an important role in energy homeostasis during fasting or periods of high energy demand. Dysregulation of ACAA1 activity can lead to metabolic disorders, such as Zellweger syndrome and other peroxisomal biogenesis disorders, characterized by impaired fatty acid oxidation and accumulation of toxic lipid intermediates. ACAA1 is also being studied for its role in the metabolic reprogramming of cancer cells, where it contributes to lipid catabolism and tumor progression.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Acetyl Coenzyme A Acyltransferase 1 (ACAA1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 28.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly182-Asn424 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACAA1
dry ice
No
availability
Shipped within 5-7 working days.
alias
ACAA, Lnc-Myd88, PTHIO, THIO
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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proveedor
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