Mouse A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Mouse A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503219
tested applications
ELISA
Description
Mouse A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse A disintegrin and metalloproteinase with thrombospondin motifs 16 concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q69Z28 |
Gene ID | 271127 |
Alias | Type 1 Motif 16,ADAMTS16s,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 16,ADAMTS-16,ADAM-TS16 |
Background | Elisa kits for ADAMTS16 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADAMTS16 (ADAM metallopeptidase with thrombospondin type 1 motif 16) is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS16 contains several characteristic domains of the ADAMTS family, including a signal peptide, a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and multiple thrombospondin type 1 (TSP1) motifs. ADAMTS16 is expressed in various tissues during development and in adulthood. It is found in tissues such as the heart, lungs, kidneys, and skeletal tissues.It may play a role in processes such as chondrogenesis and osteogenesis where it regulates ECM composition and structure. ADAMTS16 expression levels have been found to be dysregulated in various cancers, including breast cancer, ovarian cancer, and prostate cancer. Its roles in ECM remodeling and tissue development suggest potential contributions to tumor progression, invasion, and metastasis. Dysregulation of ADAMTS16 activity has been associated with musculoskeletal disorders such as osteoarthritis and intervertebral disc degeneration. In these conditions, ADAMTS16 contributes to the degradation of ECM components within cartilage and intervertebral discs, leading to tissue degeneration and joint dysfunction.
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