Mosunetuzumab
Pida mas información
935106861
info@markelab.com
Precio
375€ (100 µg)
proveedor
Abbexareference
abx831441Tested Applications
ELISA, WBreactivity
Humanstatus
This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications (RUOclonality
MonoclonalDescripción
Mosunetuzumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting CD3E/MS4A1/CD20, Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. Mosunetuzumab simultaneously binds to CD3 epsilon (CD3ε), a component of the T-cell receptor (TCR) complex, and to CD20, a B-cell surface protein expressed in a majority of B-cell malignancies. This results in crosslinking of the TCR, inducing downstream signaling events that lead to B-cell killing.
Características del producto
category
Biosimilars
host
Human
clonality
Monoclonal
reactivity
Human
immunogen target
CD3E/MS4A1/CD20
host
Human
isotype
IgG1 Kappa
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
size 1
100 µg
size 2
1 mg
expression
Recombinant
purity
> 95%
purification
Purified from cell culture supernatants by Protein A/G chromatography.
buffer
0.01 M PBS. pH 7.4.
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
dry ice
No
availability
Shipped within 7-12 working days.
alias
Biosimilars
note
CAS Number 1905409-39-3
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