Monkey Interleukin 8 / IL8 (CXCL8) Protein
234€ (5 µg)
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Name
Monkey Interleukin 8 / IL8 (CXCL8) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx261531
Tested Applications
SDS-PAGE
Description
Monkey Interleukin 8 / IL8 Protein is a recombinant chemokine.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 8 / IL8 (CXCL8) |
| Host | E. coli |
| Assay Type | Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 5-15ng/ml, corresponding to a Specific Activity of 6,667-2,IU/mg. |
| Origin | Monkey |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 97% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 25 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | IL-8 should be stored desiccated below -18°C. Upon reconstitution IL-8 should be stored at 4°C between 2-7 days and for future use below -18°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P67813 |
| Gene ID | 613028 |
| Alias | IL8,NAF,GCP1,LECT,LUCT,NAP1,GCP-1,LYNAP,MDNCF,MONAP,NAP-1,SCYB8,C-X-C motif chemokine 8,Emoctakin,Granulocyte chemotactic protein 1,Monocyte-derived neutrophil chemotactic factor |
| Background | Protein CXCL8 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. It is recommended to reconstitute the lyophilized IL-8 in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
Background
CXCL8, also known as Interleukin-8 (IL-8), is a pro-inflammatory chemokine belonging to the CXC chemokine family. It plays a critical role in immune responses by promoting the recruitment and activation of neutrophils, which are essential in the body’s response to infection and injury. CXCL8 is secreted by a wide range of cells, including macrophages, epithelial cells, endothelial cells, fibroblasts, and keratinocytes, particularly in response to inflammatory stimuli like bacterial products, oxidative stress, and pro-inflammatory cytokines such as IL-1 and TNF-α. CXCL8 is a potent chemoattractant that directs the migration of neutrophils from the bloodstream to the site of infection or tissue damage. This chemotactic activity is critical for the rapid recruitment of neutrophils, allowing them to carry out their functions in pathogen destruction and the removal of damaged cells.
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