Monkey Complement Fragment C3a (C3a) Protein

Este producto es parte de Complement C3
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481€ (50 µg)

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935106861
info@markelab.com
name
Monkey Complement Fragment C3a (C3a) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655921
tested applications
WB, SDS-PAGE

Description

Monkey Complement Fragment C3a (C3a) is a recombinant Monkey protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Complement Fragment C3a (C3a)
Host
E. coli
Origin
Monkey
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 34.3 kDa  Observed MW (SDS-PAGE): 35 kDa
Concentration: Prior to lyophilization: 50 µg/ml
Sequence Fragment: Cys693-Cys728
Tag: N-terminal His tag and GST tag
Expression
Recombinant
Purity
> 80%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.2 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ASP,C3a,C3b,AHUS5,ARMD9,CPAMD1,HEL-S-62p,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Background
Protein C3
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Complement C3 is a central component of the complement system, an essential part of the innate immune response that aids in the clearance of pathogens and the regulation of inflammation C3 is involved in all three complement pathways (classical, alternative, and lectin), playing a critical role in immune defense by promoting opsonization, cell lysis, and inflammation activation Upon cleavage into C3a and C3b, C3a acts as an inflammatory mediator, and C3b binds to pathogens to mark them for destruction by phagocytes Complement C3 deficiency or dysfunction is associated with various autoimmune diseases, such as systemic lupus erythematosus (SLE), and with susceptibility to infections C3 is also involved in the regulation of adaptive immunity, influencing antibody production and T-cell responses Its role in inflammation, pathogen clearance, and immune system regulation highlights its importance in maintaining immune balance and tissue homeostasis

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