Monkey AMBP (Alpha-1-Microglobulin/Bikunin Precursor) ELISA Kit
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Name
Monkey AMBP (Alpha-1-Microglobulin/Bikunin Precursor) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EMK0004
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Monkey |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | A0A0D9RJG8 |
| Alias | A1M,HCP,ITI,UTI,EDC1,HI30,ITIL,IATIL,ITILC,AMBP |
| Background | Elisa kits for AMBP |
| Status | RUO |
Background
Alpha-1-Microglobulin-Bikunin Precursor (AMBP) encodes a precursor protein that generates two distinct products: alpha-1-microglobulin (A1M) and bikunin. Alpha-1-microglobulin is a small glycoprotein with potent antioxidant and anti-inflammatory properties, primarily involved in scavenging free heme and protecting tissues from oxidative stress and protein damage. It also binds and removes oxidized molecules, maintaining cellular homeostasis. Bikunin, on the other hand, is a Kunitz-type protease inhibitor that regulates serine proteases, playing a key role in controlling inflammation and extracellular matrix stabilization. As part of the inter-alpha-trypsin inhibitor family, bikunin contributes to tissue repair and proteolytic balance. Both proteins are primarily produced in the liver and circulate in the blood, fulfilling complementary functions in tissue protection and repair. Dysregulation of AMBP expression has been implicated in liver diseases, chronic inflammation, and cancer, where disruptions in antioxidant defense, protease regulation, and extracellular matrix stability contribute to disease progression, highlighting its importance in maintaining physiological homeostasis.
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