TAK1 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Primary Antibodies
Polyclonal
Human
Mitogen-Activated Protein Kinase Kinase Kinase 7 (TAK1)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
TAK1
No
Shipped within 5-10 working days.
This product is for research use only.
Precio a consultar
Ver másPrecio a consultar
Ver másRabbit polyclonal antibody against TAK1 protein. Immunogen region is Internal. Specificity is as follows for the reactiv...
43.75€ (10 µg)
Ver más