Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) Antibody
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Description
MAP3K7IP3 Antibody is a Goat Polyclonal antibody against MAP3K7IP3.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) |
| Host | Goat |
| Reactivity | Human |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 257397, 66724 |
| NCBI Accession | NP_690000.2 |
| Background | Antibody anti-MAP3K7IP3 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
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Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) Antibody
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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