C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1) Antibody

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351€ (100 µg)

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935106861
info@markelab.com
name
C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx375112
tested applications
ELISA, WB, IHC, IF/ICC

Description

Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) Antibody is a Rabbit Polyclonal antibody against Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by affinity chromatography using epitope-specific immunogen.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9UQF2
Gene ID
9479
Background
Antibody anti-MAPK8IP1
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

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JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

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