Mitogen-Activated Protein Kinase 14 (MAPK14) Antibody

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Description
MAPK14 Antibody is a Mouse Monoclonal against MAPK14.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Mitogen-Activated Protein Kinase 14 (MAPK14) |
Host | Mouse |
Reactivity | Human, Mouse, Monkey, Rat |
Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Isotype | IgG1 |
Purification | Purified from ascites by Protein G chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, containing 0.05% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 1432 |
Background | Antibody anti-MAPK14 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
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MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
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