Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx033443
Tested Applications
ELISA, WB, IHC
Description
JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Immunogen: KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAPK10. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 52.6 kDa |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P53779 |
| NCBI Accession | NP_002744.1, NP_620446.1, NP_620447.1, NP_620448.1 |
| Background | Antibody anti-MAPK10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody
MAPK10 Antibody is a Rabbit Polyclonal antibody against MAPK10. The protein encoded by this gene is a member of the MAP …
Ver producto
Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multi…
Ver producto
Mitogen-Activated Protein Kinase 10 / JNK3 (MAPK10) Antibody
Rabbit polyclonal antibody against MAPK10 protein. Immunogen region is C-terminal.…
Ver producto