Minichromosome Maintenance Deficient 7 (MCM7) Antibody
169€ (20 µl)
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935106861
info@markelab.com
name
Minichromosome Maintenance Deficient 7 (MCM7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320233
tested applications
ELISA, IHC
Description
MCM7 Antibody is a Rabbit Polyclonal against MCM7.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Minichromosome Maintenance Deficient 7 (MCM7) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P33993 |
| Gene ID | 4176 |
| NCBI Accession | NP_001265524.1, NM_001278595.1, NP_005907.3, NM_005916.4 |
| OMIM | 600592 |
| Background | Antibody anti-MCM7 |
| Status | RUO |
Descripción
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Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
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