Microfibrillar Associated Protein 5 (MFAP5) Antibody
357.5€ (100 µg)
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Name
Microfibrillar Associated Protein 5 (MFAP5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx122837
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the MFAP5 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Microfibrillar Associated Protein 5 (MFAP5) Immunogen: Recombinant fragment corresponding to 25-162 AA of human MFAP5. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 19 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC005901 |
| Alias | AAT9,MP25,MAGP2,MAGP-2,MFAP-5,Microfibril-associated glycoprotein 2 |
| Background | Antibody anti-MFAP5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Microfibril Associated Protein 5 (MFAP5), also known as MAGP-2, is another extracellular matrix protein associated with microfibrils. MFAP5 is involved in maintaining the structural integrity of elastic fibers and modulating cell-matrix interactions. It plays a significant role in angiogenesis, influencing endothelial cell adhesion, migration, and survival. MFAP5 has been linked to tumor progression and metastasis, particularly in ovarian and other cancers, where it contributes to a pro-tumorigenic microenvironment. Elevated levels of MFAP5 are associated with poor prognosis in cancer due to its role in promoting angiogenesis and remodeling of the extracellular matrix. MFAP5 is also implicated in fibrotic diseases, where it affects tissue stiffness and pathological remodeling.
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