Microfibrillar Associated Protein 5 (MFAP5) Antibody
286€ (100 µl)
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935106861
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name
Microfibrillar Associated Protein 5 (MFAP5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx103845
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Microfibrillar Associated Protein 5 (MFAP5).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Microfibrillar Associated Protein 5 (MFAP5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.5-3 µg/ml, IHC: 5-30 µg/ml, IF/ICC: 5-30 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13361 |
| Alias | AAT9,MP25,MAGP2,MAGP-2,MFAP-5,Microfibril-associated glycoprotein 2 |
| Background | Antibody anti-MFAP5 |
| Status | RUO |
| Note | Concentration: 0.39 mg/ml - |
Descripción
Microfibril Associated Protein 5 (MFAP5), also known as MAGP-2, is another extracellular matrix protein associated with microfibrils. MFAP5 is involved in maintaining the structural integrity of elastic fibers and modulating cell-matrix interactions. It plays a significant role in angiogenesis, influencing endothelial cell adhesion, migration, and survival. MFAP5 has been linked to tumor progression and metastasis, particularly in ovarian and other cancers, where it contributes to a pro-tumorigenic microenvironment. Elevated levels of MFAP5 are associated with poor prognosis in cancer due to its role in promoting angiogenesis and remodeling of the extracellular matrix. MFAP5 is also implicated in fibrotic diseases, where it affects tissue stiffness and pathological remodeling.
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