Microfibrillar Associated Protein 4 (MFAP4) Antibody
286€ (100 µl)
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name
Microfibrillar Associated Protein 4 (MFAP4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx128441
tested applications
WB, IHC, IF/ICC
Description
Microfibrillar Associated Protein 4 Antibody is a Rabbit Polyclonal against Microfibrillar Associated Protein 4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Microfibrillar Associated Protein 4 (MFAP4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55083 |
| Alias | MFAP4 |
| Background | Antibody anti-MFAP4 |
| Status | RUO |
Descripción
MFAP4 is a glycoprotein that plays a key role in the structural organization and function of the extracellular matrix (ECM), particularly in tissues requiring elasticity such as blood vessels, lungs, and skin. It interacts with elastin and fibrillin-containing microfibrils to support elastic fiber assembly and stability, contributing to tissue elasticity and resilience. Beyond its structural role, MFAP4 has been implicated in mediating cellular adhesion and interactions with integrins, influencing cell migration and repair processes. Additionally, MFAP4 is being explored as a biomarker for various diseases, including fibrotic disorders, cardiovascular conditions, and liver fibrosis. Current research continues to elucidate its involvement in ECM-related pathologies and its potential as a therapeutic target for diseases linked to compromised ECM integrity.
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