Microfibrillar Associated Protein 4 (MFAP4) Antibody
292.5€ (80 µl)
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name
Microfibrillar Associated Protein 4 (MFAP4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032350
tested applications
ELISA, WB, IHC, FCM
Description
MFAP4 is a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Microfibrillar Associated Protein 4 (MFAP4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55083 |
| NCBI Accession | NP_001185624.1, NP_002395.1 |
| Alias | MFAP4 |
| Background | Antibody anti-MFAP4 |
| Status | RUO |
Descripción
MFAP4 is a glycoprotein that plays a key role in the structural organization and function of the extracellular matrix (ECM), particularly in tissues requiring elasticity such as blood vessels, lungs, and skin. It interacts with elastin and fibrillin-containing microfibrils to support elastic fiber assembly and stability, contributing to tissue elasticity and resilience. Beyond its structural role, MFAP4 has been implicated in mediating cellular adhesion and interactions with integrins, influencing cell migration and repair processes. Additionally, MFAP4 is being explored as a biomarker for various diseases, including fibrotic disorders, cardiovascular conditions, and liver fibrosis. Current research continues to elucidate its involvement in ECM-related pathologies and its potential as a therapeutic target for diseases linked to compromised ECM integrity.
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MFAP4 is a protein with similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region.
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