Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody

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195€ (20 µl)

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935106861
info@markelab.com
name
Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx004948
tested applications
ELISA, WB

Description

PRAME Antibody is a Rabbit Polyclonal antibody against PRAME. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Melanoma Antigen Preferentially Expressed In Tumors (PRAME)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P78395
Gene ID
23532
NCBI Accession
NP_006106.1
OMIM
606021
Background
Antibody anti-PRAME
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

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