Melanogenesis Associated Transcription Factor (MITF) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Melanogenesis Associated Transcription Factor (MITF) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx224457
tested applications
ELISA, WB
Description
MITF Antibody is a Mouse Monoclonal against MITF.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Melanogenesis Associated Transcription Factor (MITF) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01889 |
| Gene ID | 3106 |
| OMIM | 106300 |
| Background | Antibody anti-MITF |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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MITF antibody
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
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