MEK Kinase Kinase 3 (MAP4K3) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
MEK Kinase Kinase 3 (MAP4K3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025273
tested applications
ELISA, WB, IHC

Description

This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
MEK Kinase Kinase 3 (MAP4K3)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/1000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgM Kappa
Purification
Purified Mouse Monoclonal Antibody.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8IVH8
Background
Antibody anti-MAP4K3
Status
RUO

Descripción

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