Max-Interacting Protein 1 (MXI1) Antibody (Biotin)
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Description
MXI1 Antibody (Biotin) is a Rabbit Polyclonal against MXI1 conjugated to Biotin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Max-Interacting Protein 1 (MXI1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P50539 |
| Gene ID | 4601 |
| NCBI Accession | NP_001008541.1, NM_001008541.1, NP_005953.4, NM_005962.4 |
| OMIM | 176807 |
| Background | Antibody anti-MXI1 |
| Status | RUO |
Descripción
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Max-Interacting Protein 1 (MXI1) Antibody
MXI1 Antibody is a Rabbit Polyclonal antibody against MXI1. Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
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Max-Interacting Protein 1 (MXI1) Antibody
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
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Max-Interacting Protein 1 (MXI1) Antibody
MXI1 Antibody is a Rabbit Polyclonal against MXI1.
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