Matrix Remodelling Associated Protein 5 (MXRA5) Antibody
416€ (200 µl)
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935106861
info@markelab.com
name
Matrix Remodelling Associated Protein 5 (MXRA5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx433000
tested applications
P-ELISA, IHC
Description
MXRA5 Antibody is a Goat Polyclonal antibody against MXRA5.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Matrix Remodelling Associated Protein 5 (MXRA5) |
| Host | Goat |
| Reactivity | Human |
| Recommended Dilution | P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 25878 |
| NCBI Accession | NP_056234.2 |
| Alias | Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan,Adlican |
| Background | Antibody anti-MXRA5 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
Matrix Remodeling Associated 5 (MXRA5) is a glycoprotein involved in extracellular matrix (ECM) organization and tissue remodeling. It plays a significant role in maintaining ECM integrity, regulating cell adhesion, and modulating cellular responses during tissue repair and remodeling. MXRA5 expression is associated with processes such as wound healing, fibrosis, and inflammation, where ECM dynamics are critical. Dysregulation of MXRA5 has been linked to fibrotic diseases and cancer, particularly in the tumor microenvironment, where it promotes cell migration, invasion, and metastasis by altering ECM composition and structure. Studies suggest that MXRA5 may also influence immune responses by modulating cytokine signaling pathways. Its potential as a biomarker for certain cancers and fibrotic conditions is under investigation, and it represents a promising therapeutic target for diseases associated with abnormal ECM remodeling. Further research is required to fully understand its molecular mechanisms and functional significance in health and disease.
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