Matrix Metalloproteinase 9 (MMP9) Antibody

Este producto es parte de MMP9-Matrix Metalloproteinase 9
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364€ (100 µg)

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935106861
info@markelab.com
name
Matrix Metalloproteinase 9 (MMP9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx235247
tested applications
ELISA, WB, IHC

Description

MMP9 Antibody is a Rabbit Polyclonal against MMP9.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Matrix Metalloproteinase 9 (MMP9)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/200 - 1/500, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P14780
Alias
GELB,CLG4B,MMP-9,MANDP2,92 kDa type IV collagenase, Gelatinase B
Background
Antibody anti-MMP9
Status
RUO
Note
Concentration: 2 mg/ml - Validity: 12 months.

Descripción

Matrix metalloproteinase 9 (MMP9), also known as gelatinase B, is an enzyme belonging to the matrix metalloproteinase family. MMP-9 is a zinc-dependent endopeptidase. It is synthesized as a proenzyme, and requires activation by other proteases to become active. The active form of MMP-9 can degrade various components of the extracellular matrix, including collagen type IV, which is a major component of the basement membrane. MMP-9 is implicated in several physiological and pathological processes, including tissue remodeling, angiogenesis, wound healing, inflammation, and cancer metastasis. It is involved in the breakdown of the extracellular matrix, which is essential for processes like tissue repair and remodeling. However, dysregulation of MMP-9 activity can contribute to pathological conditions such as excessive tissue degradation, tumor invasion, and metastasis.MMP-9 activity is tightly regulated at multiple levels, including transcriptional regulation, post-translational modification, and inhibition by tissue inhibitors of metalloproteinases (TIMPs)

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