Matrix Metalloproteinase 17 (MMP17) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
Matrix Metalloproteinase 17 (MMP17) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032727
tested applications
ELISA, WB, IHC

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP17 is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMPs in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Matrix Metalloproteinase 17 (MMP17)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9ULZ9
Background
Antibody anti-MMP17
Status
RUO

Descripción

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