Matrix Metalloproteinase 14 (MMP14) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
Matrix Metalloproteinase 14 (MMP14) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032725
tested applications
ELISA, WB, IHC, FCM

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Matrix Metalloproteinase 14 (MMP14)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/2000, IHC-P: 1/25, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, FCM
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P50281
NCBI Accession
NP_004986.1
Background
Antibody anti-MMP14
Status
RUO

Descripción

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