Mannan-Binding Lectin Serine Protease 1 (MASP1) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Mannan-Binding Lectin Serine Protease 1 (MASP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455422
tested applications
ELISA, WB, IHC
Description
Mannan-Binding Lectin Serine Protease 1 (MASP1) Antibody is a Rabbit polyclonal antibody for the detection of Human Mannan-Binding Lectin Serine Protease 1 (MASP1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mannan-Binding Lectin Serine Protease 1 (MASP1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48740 |
| Gene ID | 5648 |
| NCBI Accession | NP_001027019.1 |
| Background | Antibody anti-MASP1 |
| Status | RUO |
Descripción
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Human MASP1 (Mannan-binding lectin serine protease 1) ELISA Kit
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MASP1 antibody
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin(MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
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